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qPCR validation of differentially expressed genes. ( A ) <t>GDF5</t> . ( B ) CCN5 . ( C ) SKIL . For each gene, cumulative results ( n = 5 donors) are showed, together with donors clustered by response to miRNA inhibitor treatment: responders (#162, #217, #255) and non-responders (#152, #157). * p < 0.05
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qPCR validation of differentially expressed genes. ( A ) <t>GDF5</t> . ( B ) CCN5 . ( C ) SKIL . For each gene, cumulative results ( n = 5 donors) are showed, together with donors clustered by response to miRNA inhibitor treatment: responders (#162, #217, #255) and non-responders (#152, #157). * p < 0.05
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qPCR validation of differentially expressed genes. ( A ) <t>GDF5</t> . ( B ) CCN5 . ( C ) SKIL . For each gene, cumulative results ( n = 5 donors) are showed, together with donors clustered by response to miRNA inhibitor treatment: responders (#162, #217, #255) and non-responders (#152, #157). * p < 0.05
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qPCR validation of differentially expressed genes. ( A ) <t>GDF5</t> . ( B ) CCN5 . ( C ) SKIL . For each gene, cumulative results ( n = 5 donors) are showed, together with donors clustered by response to miRNA inhibitor treatment: responders (#162, #217, #255) and non-responders (#152, #157). * p < 0.05
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qPCR validation of differentially expressed genes. ( A ) GDF5 . ( B ) CCN5 . ( C ) SKIL . For each gene, cumulative results ( n = 5 donors) are showed, together with donors clustered by response to miRNA inhibitor treatment: responders (#162, #217, #255) and non-responders (#152, #157). * p < 0.05

Journal: Stem Cell Research & Therapy

Article Title: Donor-dependent regulation of type II and X collagen deposition by early modulation of miR-335-5p and miR-1246 during chondrogenic commitment

doi: 10.1186/s13287-025-04589-8

Figure Lengend Snippet: qPCR validation of differentially expressed genes. ( A ) GDF5 . ( B ) CCN5 . ( C ) SKIL . For each gene, cumulative results ( n = 5 donors) are showed, together with donors clustered by response to miRNA inhibitor treatment: responders (#162, #217, #255) and non-responders (#152, #157). * p < 0.05

Article Snippet: GDF5 , Hs00167060_m1 , , .

Techniques: Biomarker Discovery